English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Chronic fatigue syndrome (CFS) is the most severe condition among fatigue-associated disease, which impairs seriously quality of life (QOL) in aspects of physical, mental, and occupational wellbeing. This disease is characterized by profound fatigue persisting over six months, and other symptoms such as cognitive dysfunction, sleep disturbance and multiple pain. CFS thus often leads social isolation, and is related with high risk of suicide by seven fold. The prevalence of CFS is reported as approximately 1% in general population worldwide including in Korea. The proposed pathological mechanisms include abnormalities in autonomic nervous system function, immunological response or hypothalamic-pituitary-adrenal (HPA) axis against stress. However, its etiology is not understood yet, and no medications or therapeutics have been approved to date. Although a large-scale clinical study (called the PACE trial) recommended Minireview for Chronic Fatigue Syndrome and its Medical Attention recently