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The present work includes synthesis of a series of amide derivatives of glyphosate and their characterization. The structure analysis of these new derivatives was done with the help of FTIR and 1H NMR, Further, their herbicidal activity was analyzed on one of the common weeds (Parthenium hysterophorus). Under the influence of amide derivatives of glyphosate it was found that the chlorophyll content (Chlorophyll a, Chlorophyll b and total Chlorophyll content) of the weed was found to lessen than the control. Moreover, these synthesized derivatives are less polar as compared to the parent glyphosate molecule thereby can emphatically reduce the problem of their leaching into the groundwater.

Synthesis, Characterization and Herbicidal Activity of Amide Derivatives of Glyphosate