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Spiroborate ester of curcumin with salicylic acid (CBS) has been synthesized and characterized by different spectral techniques.The non-isothermal thermogravimetric method was used to study the thermal decomposition of CBS at the heating rate of 10 °C min-1 in nitrogen atmosphere. Hydrolytic stability was studied in aqueous acetone system with different percentages of water and temperature. The activation energies associated with the hydrolysis were evaluated using Arrhenius equation and the corresponding values of thermodynamic parameters were determined using Eyring equation. The possible mechanistic route for the hydrolysis of the complex was proposed.

Kinetic Analysis of Thermal and Hydrolytic Decomposition of Spiroborate Ester of Curcumin with Salicylic Acid