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Modified Fe 3 O 4 nanoparticles with (3-aminopropyl) triethoxysilane (APTES) were synthesized by post grafting method for loading the anti-inflammatory drug: (+)-(S)-2-(6- methoxynaphthalen-2-yl) propanoic acid -Naproxen and (RS) 2-(3-benzoylphenyl)-propionic acid -Ketoprofen. The prepared samples were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Field Emission Scanning Electron Microscopy (FE- SEM), Energy Dispersive X-Ray Spectroscopy (EDX), Vibrating sample magnetometer (VSM), and Dynamic light scattering (DLS) diagrams. These nanoparticles have surface with free - NH2 groups can carry out ionic interaction with carboxylic groups and act as a carrier of drugs.

oriental journal of chemistry/oriental journal of chemistry

Fe3O4 nanoparticles modified with APTES as the carrier for (+)-(S)-2-(6-methoxynaphthalen-2-yl) propanoic acid (Naproxen) and (RS) 2-(3-benzoylphenyl)-propionic acid (Ketoprofen) drug