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Cervical cancer is among the common gynecologic malignancies effective and well developed cytologic screening programs are not available in developing countries. This study is to compare screening and diagnostic culposcopy. In a prospective cross-sectional study 2235 screening and 2318 diagnostic colposcopies were compared. Diagnostic colposcopy indications included chronic vaginal discharge, abnormal cervix, positive VIA test, abnormal cytology, postcoital bleeding and intermenstrual bleeding. CIN2 as more pathology findings were compared in two groups. High score colposcopy were found in 1084 out of 2235 (48.5%) screening cases and 1476 out of 2318 (63.7%) diagnostic group. Pathologic result of CIN2 as more was observed in 45 (2.3%) of screening and 110 (5.3%) of diagnostic colposcopies. Cases finding of diagnostic colposcopy was significantly more in diagnostic group in comparision to screening cases. Decision regarding screening colposcopy needs more studies in different aspects specially cast-benefit of alternative methods.

Comparison of Screening Colposcopy with Diagnostic Colposcopy