English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The effect of ethanolic extract of Terminalia chebula was tested on hematological complications induced by doxorubicin (DXR) in male and female rats. Hematological parameters were evaluated by estimating the hemoglobin content and total leucocytes count. The antioxidant assay was done by finding the serum catalase level. The results of the study was analyzed by Two-way Anova and Bonferroni tests and p<0.05 was considered to indicate the significance of the results. Our data indicated DXR at 2.5 mg/kg significantly (p<0.001) decreased the hemoglobin content, total WBC count and serum catalase level compared to control groups in both male and female rats. Administration of Terminalia chebula extract at 0.5 and 1 g/ kg significantly (p<0.05) improved the level of hemoglobin content and total WBC count and elevated the catalase concentration compared to DXR. The results suggest that co-administration of Terminalia chebula can prevent the hematological complications of doxorubicin possibly by elevating the antioxidant status.

Ameliorative Effect of Terminalia Chebula on Hematological Complications Induced by Doxorubicin