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The objective of the study was to screening and compare anti bacterial activity of Hoya carnosa leaves extract, Chloramphenicol 1% and Ciprofloxacin against bacteria Staphylococcus and Pseudomonas aeruginosa that cause benign type Chronic Suppurative Otitis Media (CSOM). Hoya carnosa leaves extract, Chloramphenicol 1 % and Ciprofloxacin were subjected to screening and compare their antibacterial activity against two strains of bacteria species, Staphylococcus aureus, Pseudomonas aeruginosa that taken from culture ears secretions of patients active benign type of CSOM. The study using standard protocol Disc Diffusion Method (DDM). Antibacterial activity were assessed by the presence or absence of inhibition zones and minimal inhibitor capacity (MIC) values. Ciprofloxacin had the most powerful bacterial activity in Disc Diffusion Methods (DDM) with mean rank 13, then Chloramphenicol with mean rank 8 and the weakest is the Hoya carnosa leaves extract with mean rank 3. There significant differences among antibacterial activity of Hoya carnosa leaves extract, Chloramphenicol 1% and topical Ciprofloxacin against two strains of bacteria species, Staphylococcus aureus and Pseudomonas aeruginosa.

biomedical and pharmacology journal/biomedical and pharmacology journal

Antibacterial Activity Extract Hoya Carnosa Leaves, Chloramphenicol 1% and Ciprofloxacin against Staphylococcus aureus and Pseudomonas aeruginosa that caused benign type Chronic Suppurative Otitis Media (Disc Diffusion Method)