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One of modern vitamin sources for lactating cows is Lipovitam-beta. It was made on liposomes’ basis and can provide maximum vitamins’ assimilation by the whole organism’s cells. Aim of investigation: to estimate Lipovitam-beta impact on the indices of hemostasis system and blood rheology of high-productive cows during the first 5 months of lactation. We examined 207 healthy black-many coloured cows having begun the process of lactation. They were of the 3-4th calving and were kept in conditions of fastened support having traditional ration. The animals were casually divided into experimental and control groups. in the experimental group (104 cows) we examined the impact of Lipovitam-beta feeding on the basis of 1 capsule (0,17gr) on 30 kg of body mass once in 5 days during the first 5 months of lactation on accountable indices. The control group was composed of 103 lactating cows. We estimated the basic indices of hemostasis, blood viscosity, erythrocytes’ aggregation and deformability on the 5th day and in 5 months of lactation. Lipovitam-beta application led in case of cows from experimental group to reliable decrease of spontaneous and stimulated platelets’ aggregation and weakening of plasma hemostasis activity. On the background of Lipovitam-beta feeding the cows were found to have decrease of blood viscosity and erythrocytes’ aggregation index what was accompanied by increase of erythrocytes’ deformability index. The cows from the control group during the first 5 months of lactation were noted to have rise of platelets’ aggregation and increase of hemocoagulation. It was accompanied by the tendency to increasing of blood viscosity and erythrocytes’ aggregation with inclination to the decrease of their deformability. High-productive cows by the middle of lactation are noted to have developing tendency to hemostasis activation and worsening of blood rheological features what weakens microcirculation processes and may be one of the factors gradually blocking lactation. Lipovitam-beta application to lactating cows led to activity decrease of plasma hemostasis and platelets, increase of rheological features what can positively influence microcirculation and the level of dairy producing capasity.

biomedical and pharmacology journal/biomedical and pharmacology journal

Hemostasis and Rheological Blood Features Dynamics of Black-many Coloured Lactating Cows at the Inclusion into their Ration of Antioxidant Lipisomal Preparation “Lipovitam-beta”