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The aim of this study was to evaluate the influence to acute exercises performed in different intensities with volume equalized (5 km) on indices of cardio-inflammatory health. Twelve physically active male subjects (age, 23.22±5.47 years; height, 174.75±5.80 m; weight, 75.13±6.61 kg; maximal oxygen uptake, 52.92 mL/kg/min), after determination of peak oxygen uptake (VO 2Peak ) and the speed associated with VO 2Peak (sVO 2Peak ), completed two randomly experimental trials: high-intensity intermittent exercise (HIIE: 1:1 at 100% sVO 2Peak ) and moderate-intensity continuous exercise (MICE: 70% sVO 2Peak ). Brain-derived neurotrophic factor (BDNF), adiponectin and plasminogen inhibitor-1 (PAI-1) data were analyzed pre, immediately, and 60 min after the exercise session. Statistical analysis comparisons between moments and between HIIE and MICE were performed using a mixed model and statistical and significance was set at &lt;5%. PAI-1 presented an effect for time from pre to immediately after exercise moment ( P &lt;0.018) and from immediately to 60 min after exercise moment ( P &lt;0.001) only in MICE. BDNF presented an effect for time from pre to immediately after exercise to HIIE ( P &lt;0.022) and from immediately to 60 min after exercise to MICE ( P &lt;0.034). HIIE promotes BDNF increase and that there is negative correlation between PAI-1 concentrations and BDNF in both protocols in healthy sportsmen, favoring an anti-atherogenic profile.

Influence to high-intensity intermittent and moderate-intensity continuous exercise on indices of cardio-inflammatory health in men