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Rectal applications are not recommended in patients who receive chemotherapy for malignant hematological diseases as they can cause serious complications, especially during neutropenic periods. Minimal mucosal damage during a rectal application can lead to cellulitis, abscess formation and fi stulization. Our case is a 7-year-old boy who had been newly diagnosed with acute lymphoblastic leukemia. While he was undergoing induction therapy, rectal enema was administered at home because of two days of constipation after discharge from the hospital. The patient developed severe necrotizing perianal cellulitis and needed wide debridement, colostomy opening and autologous skin engraftment for treatment. We decided to present our case to once again emphasize the importance of this topic.

Severe Necrotizing Perianal Cellulitis in a Child with Acute Lymphoblastic Leukemia that Developed After Rectal Enema Use