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Nine dogs with flea allergic dermatitis diagnosed by immediate-type intradermal test, were injected with a self-made allergen, which was prepared from the whole flea by ultrasonication, filtration and incubation at 65•Ž. Nine dogs were subcutaneously injected with 1ml of a 1:5,000(W/V) dilution of the allergen once a week. Six and 3 dogs received 12 or more and 4 injections, respectively. Six (66.7%) of 9 dogs responded to the treatment with a mean improvement rate of 73%(33-100%). Slight increases in indirect hemagglutination titers were demonstrated in 3 dogs, whereas 2 dogs showed decreases in Prausnits-Kustner titers after the treatment.-

Immune Treatment of Flea Allergic Dermatitis of Dogs with Flea Extract