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Serum selenium (Se) levels and blood glutathione peroxidase (GSH-Px) activities in pregnant ewes, to which sodium selenite (as E-Se contained tocopherol) or seleno-L-methionine was injected intramuscularly with Se of 0.1 mg/kg body weight at 2-week intervals one month prior to parturition, were examined. Serum Se levels increased markedly after administration of Se, and blood GSH-Px activities, showing significantly higher levels in ewes injected with selenomethionine, increased gradually after 2 weeks. Serum Se levels and blood GSH-Px activities in the lambs born to these ewes were high, especially in lambs administered with selenomethionine. Nonetheless red blood cell and serum tocopherol levels in ewes and newborn lambs showed no difference in each group. Se concentrations in the milk of ewes injected with Se were high especially in the ewes with selenomethionine. It was concluded that selenomethionine was more utilizable in GSH-Px and passable through the placenta than sodium selenite.

Changes of Serum Selenium Levels and Blood Glutathione Peroxidase Activities in Pregnant Ewes Injected with Organic and Inorganic Selenium