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Protease Antibody in Blood of Sows Infected with Corynebacterium pyogenes and Their Young FuMro HIASA, et al. (Central Laboratory, Zenno Feed and Animal Industry Corporation, Tsukuba, Ibaraki 300-42) SUMMARY To develop any antemortem serodiagnosis of a porcine apostematous disease caused by Corynebacterium pyogenes, transmission of protease antibody against this organism from 7 sows positive for this antibody to their young was studied by means of the gel precipitin reaction. 1. It was frequent for 1/2-1/3 of the antibody titer of the sow at the time of parturition to be transferred to their young. 2. Such low titer of transferred antibody as 1:2 disappeared by 3 weeks of age. When the titer of this antibody was 1:8 and 1:16 or 1:32, it disappeared completely by 5-10 and 11 weeks of oge, respectively. 3. No antibody was detected from the umbilical cord blood of fetuses borne by two sows in which abscess was formed and the protease antibody titer 1:32 and 1:125, respectively. 4. When the sera of antibody-positive sows and their young were subjected to the gel precipitin reaction with Sephadex G-200, protease antibody against C. pyogenes was found to have its activity in such fraction as presumed to be IgG.