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The research was conducted the effect of chitosan on rats blood alteration that induced arthtritis. In addition, the research used pre-post test group control design. than used  was divided into groups (n=6) including normal groups, positive control, negatif control, and  groups were treated by  khitosan at varian 50 mg/200gBB and 100 mg/200gBB doses. Adjuvant-induced was developed using complete Freund’s Adjuvant on 1 st day, than 17-47 th days after treated given appropriate their groups. To evaluate did blodd counter on 0, 16 th ,and 47 th days after treated with otomatic optic dan electronic resisten method. Than analyzed using ANOVA test and paired t-test (p 0,05) and PLCR 35,66% (p<0,05). In additional research, khitosan 50 mg/200gBW fit to complete blood of the rheumatoid arthritic mouse well.

Pengaruh Sintesis Kitosan dari Cangkang Udang terhadap Red Blood Cell, Hemoglobin, dan Trombosit pada model Rheumatoid Arthtritis yang diinduksi CFA