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The snail Cepaea hortensis O-dealkylates sulfadimethoxine at the 2- and 6-position, the 2-position being favoured. Sulfadimethoxine is also acetylated, while no measurable acetylation of the hydroxy (= demethyl) metabolites took place.

O-demethylation and N4-acetylation of sulfadimethoxine by the snail Cepaea hortensis.