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Rainbow trout (Oncorhynchus mykiss) head kidney phagocytes precultured with a synthetic cytidine-phosphate-guanosine (CpG) oligodeoxynucleotide (ODN) displayed significantly higher phagocytic activity against Vibrio ordalii than phagocytes precultured with non-CpG ODN. However, head kidney phagocytes precultured with CpG ODN did not show enhanced phagocytic activity against polystyrene particles.

journal of veterinary medical science

In vitro Enhancement by CpG ODN of Phagocytic Activity of Rainbow Trout Head Kidney Phagocytes against Fish Pathogen Vibrio ordalii, but not against Polystyrene Particles