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On June and August in 1989, cutaneous hemorrhagic parafilariasis was found in two cattle among 30 pregnant dairy cattle transported from Hokkaido to Chiba Prefecture. One adult female worm each was recovered from the blood spot in both cattle. Ivermectin oral administration, dosage rate of 200 micrograms/kg body weight, had no effect on the occurrence of the blood spots. Topical application of levamisole on a blood spot at a 2.5% concentration showed to stop the bleeding within a few minutes after treatment. This method was very easy to use at the farm situation where cutaneous hemorrhagic parafilariasis sporadically occurred. The disease has not been found in Chiba Prefecture on a whole since those cases in 1989.

Two Cases of Parafilariasis in Dairy Cattle and Treatment of Hemorrhage with Levamisole Topical Application.