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Rinderpest (RP) virus is classified into the Morbillivirus genus belong{ng to Paramyxovirus family, It is generally considered that RP virus has only one serotype. However, it has becn reported by some researchers that there are sorne antigenic differences among RP virus strains [1, 4, 6, 9]. In this report, the two RP vaccine strains, Kabete "O" (RBOK) strain [51 and lapinized and avianized (LAAKO) strain [21 were compared by neutralization test (NT) using the sera from calves vaccinated with each live vaccine, RBOK strain is most commonly used in RP epidemlc countries worldwide, while Vero cell-adapted RBOK strain was recently develeped for vaccine use [3]. On the other hand, the LA-AKO strain has been used in Japan as a tissue culture vaccine produced in Vero cells [8]. RBOK strain which had undergone 95 passages through bovine kidney (BK) cells was kindly supplied by the Animal Virus Research Center, Pirbright, England, and subcultured once in BK cells in our laboratory. LA-AKO strain has been stored as an original vaccine seed which had undergone 456 passages through embryonating chicken eggs in our laboratory and further 5passages in Vero

Comparison between the antigenicity of two rinderpest vaccine strains using the neutralization test.