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Animal studies indicate polybrominated diphenyl ethers (PBDEs) are endocrine disruptors, potentially affecting the role of thyroid hormones in regulating the reproductive cycle and fertility. The compounds also have been associated with delayed puberty and altered estradiol levels in female animals. Very little is known about the potential effects of PBDEs on human reproductive health, though, and a new study is the first to characterize a specific concern—a relationship between PBDE blood concentrations and a delay in achieving pregnancy [EHP 118:699–704; Harley et al.].

Pregnant Pause: Does Maternal PBDE Exposure Extend Time to Pregnancy?