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Background: Cardiovascular diseases (CVDs) are the primary cause of mortality worldwide with 17.3 million deaths per year and an estimation of 23.6 million in 2030, placing it as a relevant issue for the public health system. Objectives: This study aimed to assess the Remodeling Index (RI) and its relation to coronary heart disease in patient with type 2 diabetes mellitus (T2DM) by multi-slice coronary CT angiography (MSCTA). Patients and methods: This prospective observational study was conducted in Cardiology Department and Radiology Department in El-Agouza, Academy, Nasr City Police Hospital. The study included 250 patients with coronary remodeling of which 200 patients with type 2 diabetes (group I) and 50 are non-diabetics (group II) matched in age and sex with the patients’ group I (P > 0.05). All patients referred for MSCT coronary angiography. Results: As regard remodeling index of the two groups were 1.11 ± 0.34 and 0.81 ± 0.29 in groups (I) and (II), respectively. They showed a statistically highly significant difference between the two groups (p 75th percentile was found in 26% of group (I) and not found in group (II) and they showed a statistically very highly significant difference (p < 0.001). Conclusion: Patients with T2DM are susceptible to premature CAD with more calcified and non-calcified plaques. Early prevention program using computed tomography angiography might be helpful in identifying diabetic patients with subclinical atherosclerosis.

Assessment of remodeling index and its relation to coronary heart disease in patients with types 2 diabetes by MDCT coronary angiography