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Background: Regional anesthesia is a preferred technique for ophthalmic surgery. It is safe, inexpensive and provides efficient ocular anesthesia for ophthalmic surgery. It is associated with less hemodynamic instability, less respiratory depression, better postoperative pain relief, and less nausea and vomiting compared to general anesthesia. Objectives: The aim of the study was to compare the safety and efficacy of the use of Magnesium sulfate versus that of Rocuronium versus Dexmedetomidine as an adjuvant to the local anesthetic in peribulbar anesthesia. It is characterized by generating optimal operating conditions for eye surgery in terms of akinesia, analgesia, incidence of complications, as well as induction of patient and surgeon satisfaction. Patients and Methods: The present study included100 patients of the American Society of Anesthesiology (ASA), physical status I, II, III or IV of both sex, (20-80) years old and undergoing to anterior and posterior segment surgeries. Informed written consent from all patients was taken after approval of Al-Azhar University Ethical Committee. Results: Evaluation of the globe akinesia was done at (2.5),(5),(7.5),and(10) min. after injection. The onset of motor block showed a statistically significant difference between the four groups, the rocrounium group showed more rapid onset of motor block then dexmedtomedine group then magnisum sulphate group then lastly the control group. Conclusion: The present study concluded that using Rocuronium as an additive to local anathestic drugs in peribublar block it makes onset of block more rapid and dense but it has less effect on analgesic aspect. On the other hand, when Dexmedetomidine or Magnesium sulfate were used as additive they increased analgesic effect of local anathestic and decreased the need for early postoperative rescue analgesia, as well as fastening the onset of block but to a lesser extent less than Rocuronium as an additive to local anathestic.

the egyptian journal of hospital medicine

Clinical comparative study between Magnesium sulphate versus Rocuronium versus Dexmedetomidine as adjuvants for local anesthetic in peribulbar block for eye surgeries