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Objectives: To evaluate the influence of susceptibility-weighted imaging (SWI) on detection rates and reported results in the diagnosis of various brain conditions, compared with conventional magnetic resonance imaging (MRI). Methods: Brain MRI was obtained for various indications in 251 patients (115 male, 136 female). The mean age of the patients was 49.91 years. Two neuroradiologists independently evaluated the detection rates and reported results of brain MRI with and without SWI sequences. Statistical analysis was performed by using McNemar’s Chi-square test and Cohen’s kappa coefficient. Results: Neuroradiologists 1 and 2 considered SWI to have influenced detection in 51% and 53% of patients, respectively, and to have influenced the reported results in 20% and 18% of patients, respectively. SWI had the strongest influence in the detection rates of vascular disease in 22 patients (100%) and calcification and abscesses in two patients (100%). SWI had the strongest influence on the reported results of vascular disease in 20 patients (91%) and of neurodegenerative / demyelinating in 11 patients (79%). There was excellent inter-observer reliability between neuroradiologists 1 and 2 (kappa value = 0.883-0.936). Conclusion: SWI is a helpful technique in routine brain MRI sequences, and influences the detection rates and reported results, especially for vascular disease, microbleeds, infection, neurodegenerative / demyelinating disease, and evaluation of intratumoral components. SWI should be added to conventional MRI sequences.

Influence of Susceptibility-weighted Imaging on Brain Magnetic Resonance Imaging Diagnostics