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I mprovements in our understanding of the molecular mechanisms of cancer combined with advances in genome sequencing have provided revolutionary new therapeutic options for several hard-to-treat tumors in recent decades. For other challenging tumor types these advancements have served only to highlight their signifcant complexity and, despite the development of novel treatments, there has been limited improvement in prognosis.

Glioblastoma, bone sarcoma, and liver cancer: tough battles rage on for some tumors