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The effects of partial obstruction of blood flow and mixed type acidosis on the conduction spinal evoked potentials (C-SEP) were studied in cats anaesthetized with sodium pentobarbitone and immobilized with d-tubocurarine. Following the ligation of some intercostal arteries, changes in the C-SEP occurred: the amplitudes showed either an increase or a decrease, while the latencies were uniformly prolonged. Mixed-type acidosis resulting from a decrease in the respiratory minute volume led to a decrease in the amplitudes and an increase in the latencies. The above findings indicate that not only mechanical (obstruction of the blood flow) but also metabolic (mixed-type) factors lead to changes in the C-SEP. It is therefore important to take these factors into account and the waveform of the C-SEP should be interpreted in terms of amplitude and latency.

Changes in spinal evoked potentials caused by spinal blood flow obstruction and acidosis.