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Atrial natriuretic peptide (ANP) plays important roles in the regulation of cardiovascular and renal homeostasis. Furthermore, several studies have shown that ANP may have anti-inflammatory activities. We hypothesized that ANP may alleviate cardiovascular and/or metabolic disorders in rats with lipopolysaccharide (LPS)-induced endotoxemia.

journal of nippon medical school

Atrial Natriuretic Peptide Alleviates Cardiovascular and Metabolic Disorders in a Rat Endotoxemia Model: A Possible Role for Its Anti-inflammatory Properties