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Blood vessels begin to form from sprouts of endothelial cells, and these projections determine various morphologic features of the vasculature. Cell movements are a primary determinant of vascular patterning during blood-vessel formation. In this photogravure, endothelial cell motility was shown at the single-cell level, and dynamic and complex cell selectivity in direction and in migration distance was demonstrated in vitro.

Dynamic and Complex Cell Movement during Formation of Vascular Structures with the Fibrin Bead Assay