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the other form works as a competitive inhibitor, for example carnitine. Optically active 3-halolactic acid and its derivative, glycidic acid, are useful building blocks for the asymmetric synthesis of pharmaceuticals, such as ^-adrenergic blocking agents, leukotrienes, and prostaglandins. 2-Halo acid dehalogenase (EC 3.8.1.2) catalyzes hydrolytic release of halogen from 2-halocarboxylie acids, and produces 2-hydroxy acids with inversion of the configuration. L-2-Halo acid dehalogenase acts on the L-isomer of 2-halocarboxylic acids and produces d-2-

A new approach for enzymatic synthesis of D-3-chlorolactic acid from racemic 2,3-dichloropropionic acid by halo acid dehalogenase.