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which were of the purest grades available from commercial sources. About 3.0mg of each compound was put into a small quartz test tube (4mm O.D. and 0.5mm thick). The tube was evacuated to about 10"1 mmHgand then sealed with a flame at a length of about 40mm.Pyrolysis was performed in a Packard Tri-Carb Combustion Furnace, Model 325. Each sealed tube was placed in the middle of the pyrolysis column and heated at 500 to 800°C for 1 min. After removal and cooling, the tube was broken and its contents were dissolved in 800 ^1 of dimethyl sulfoxide (DMSO). Mutation assays with and without PCB-induced rat

Mutagenicity of pyrolyzates of natural substances toward Salmonella typhimurium TA97.