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Two potent gastroprotective substances against experimental gastric ulcers in rats induced by stress and five of their analogues were isolated from the culture broth of bacterial strain AI-77 which was classified taxonomically as Bacillus pumilus. Physico-chemical properties and pharmacological activities of the seven compounds were examined and compared with each other.

Studies on AI-77s, microbial products with pharmacological activities. Part I. Production, isolation and pharmacological studies of AI-77s.