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The β-glucan freeze-thaw gel has been used as a carrier to release curcumin. The freeze-dried gel has the ideal sustained release following 5% β-glucan solution by adding 1% β-glucan quality curcumin, repeated freezing and thawing 8 times. The Peppas equation can significantly describe the release mechanism of curcumin in the β-glucan gel. This study further shows that the release of curcumin in the oat β-glucan gel is the Fick diffusion mechanism and coated barley β-glucan is a non-Fick release. Trying to use β-glucan as a completely natural drug delivery carrier opens up new ideas for the use of β-glucan.

Preparation of Grain β-glucan Gel and Characteristics of Its Slow-release