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Drug-induced autoimmune hepatitis (DI-AIH) is a poorly defined, underreported liver disorder. This report describes a rare case of anti-TNF DI-AIH in a patient with Crohn’s disease resulting in acute liver failure requiring orthotopic liver transplantation in which a novel technique of leveraging a delayed abdominal fascial closure to perform ileocolonic anastomotic revision was used.

american journal of medical case reports

Unique Immediate Postoperative Management of Crohn’s Disease in a Patient with Autoimmune Hepatitis-Like Drug-Induced Liver Injury from Infliximab Requiring Liver Transplantation