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Brain is phenomenally plastic and exhibits this capacity well into adulthood. Neuronal plasticity can be studied by using different adaptation protocols. Post-adaptation neurons typically show attractive and repulsive shifts even though challenged by the same adapter. Using orientation columns as a paradigm, we argue and suggest that repulsive shifts are essentially fundamental to preserve the functional organization of the cortex, and thus, maintaining the functional homeostasis of the brain.

The referential brain: why do some neurons learn and some do not?