English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Purpose: To determine the safety and efficacy of corneal photovitrification (CPV), a new corneal laser procedure, for vision improvement in patients with late stage dry age-related macular degeneration (AMD). Design:  Retrospective observational cohort study Participants:  32 eyes of 17 patients with late stage dry AMD; each eye received a single CPV corneal laser procedure and had 12 months (12m) post-treatment (Tx) follow-up. Methods: Preand post-Tx examinations included slit-lamp biomicroscopy, subjective manifest refraction, best corrected distance and near visual acuity (BCDVA and BCNVA), and potential visual acuity (PVA). Additional examinations including contrast sensitivity (CS), corneal topography (CT), ray tracing aberrometry (RTA) and microperimetry (MP) were obtained for a subgroup (n=12) of eyes. Main Outcome Measures:  BCDVA, BCNVA, PVA, CS, CT, RTA and MP measurements Results:  Safety – There were no complications or adverse events. Efficacy – Mean (± SD) BCDVA improved significantly (p < 0.004) from 20/238 (1.08 logMAR) at baseline to 20/144 (0.86 logMAR) at 12m postTx corresponding to 11.0 (± 13.1) letters gained.  Mean contrast sensitivity improved significantly (p < 0.05) by a factor of 1.86 from baseline at 12m post-Tx. Conclusions:  Subject to the limitation of a small sample size, this pilot study indicates that the CPV corneal laser procedure is safe and efficacious for vision improvement in patients with late stage dry Open Peer Review Reviewer Status AWAITING PEER REVIEW Any reports and responses or comments on the article can be found at the end of the article. Page 1 of 11 F1000Research 2020, 9:1500 Last updated: 23 DEC 2020

f1000research

Corneal laser procedure for vision improvement in patients with late stage dry age-related macular degeneration - a retrospective observational cohort study