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The distribution of lost chromosomes in Patau's grouping was studied in cells with 45 normal chromosome complements. A total of 132 metaphase plates were karyotyped from cultured peripheral leukocytes and 35 from bone marrow cells. The pattern of missing chromosomes was found to be significantly different from expectation based on the number of chromosomes per group. Unusually low incidences of missing chromosomes of groups A, B and F were discovered.

A STUDY ON ANEUPLOIDY IN HUMAN PERIPHERAL LEUKOCYTES AND BONE MARROW CELLS