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Although sickle-cell anemia (SCA) is common in black Americans, Sub-Saharan Africa and in the Mediterranean area, the disease is rare in the temperate climate zone. The manifestations of the disease are related mainly to the production of abnormal hemoglobin that leads to organ ischemia and increased susceptibility to infection caused by functional asplenia.

Gruźlicze zapalenie kręgosłupa u chorej na anemię sierpowatokrwinkową - obraz w Tomografii Komputerowej