English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

BACKGROUND This study aimed to investigate the clinical significance of postoperative serum levels of interleukin-1ß (IL-1ß), interleukin-17 (IL-17), and tumor necrosis factor-alpha (TNF-alpha) in patients who required hip replacement surgery for traumatic fractured neck of femur. MATERIAL AND METHODS A retrospective study included 180 patients who had hip replacement surgery for traumatic fractured neck of femur and a control group of 100 patients. Differences between the two groups were compared for serum levels of IL-1ß, IL-17, and TNF-alpha, and the Harris Hip Score (HHS) (maximum 100 points) using Pearson's correlation. RESULTS Serum levels of IL-1ß, IL-17, and TNF-alpha in the control group were significantly lower than those in the study group (P&lt;0.05). According to the HHS, there were 53 patients in the excellent group, 65 patients in the good group, 43 patients in the fair group and 19 patients in the poor group. Postoperative indicator analysis showed significant differences in IL-1ß, IL-17, and TNF-alpha levels between the four groups (P&lt;0.05). Clinical indicators increased from the excellent group to the poor group, with significant differences between the four groups (P&lt;0.05). Postoperative levels of IL-1ß, IL-17, and TNF-alpha were significantly decreased (P&lt;0.05). Pearson's correlation analysis showed a significant correlation with the clinical indicators (P&lt;0.05). CONCLUSIONS In patients with hip replacement surgery for traumatic fractured neck of femur, measurement of postoperative serum levels of IL-1ß, IL-17, and TNF-alpha were shown to be potential prognostic indicators.

medical science monitor

Postoperative Serum Levels of Interleukin-1β (IL-1β), Interleukin-17 (IL-17), and Tumor Necrosis Factor-α (TNF-α) in Patients Following Hip Replacement Surgery for Traumatic Fractured Femoral Neck: A Retrospective Study