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Hemodynamically significant patent ductus arteriosus (hsPDA) leads to injury in tissues/organs by reducing perfusion of organs and causing oxidative stress. The purpose of this study was to evaluate the oxidant/antioxidant status in preterm infants with hsPDA by measuring the total antioxidant capacity and total oxidant status and to assess neuronal damage due to oxidant stress related to hsPDA.

Impact of Patent Ductus Arterıosus and Subsequent Therapy with Ibuprofen on The Release of S-100B and Oxıdatıve Stress Index in Preterm Infants