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The convergence of nutritional, genetic, and inflammatory factors plays a significant role in the pathophysiology of squamous cell esophageal cancer (SCEC). The parameters of inflammation, indices of nutritional status, and adipocyte-derived hormones such as leptin, adiponectin, and resistin have been shown to be prognostic factors in some gastrointestinal and pancreatic cancers.

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Serum Adiponectin Relates to Shortened Overall Survival in Men with Squamous Cell Esophageal Cancer Treated with Preoperative Concurrent Chemoradiotherapy: A Pilot Study