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Ketamine hydrochloride alone was an effective analgesic in the Mongolian gerbil. In 28 young adult animals of both sexes (bodyweight 45-68 g) intramuscular injection of 44 mg/kg produced analgesia in about 83 seconds. Deep surgical anaesthesia could be readily achieved in about 12 min from start when methoxyflurane was administered by nasal cone 5 min after ketamine injection, and the surgical level was maintained arbitrarily for about 40 min during part of which laparotomy was performed. Induction of deep anaesthesia was smooth and recovery occurred uneventfully. The combination of ketamine and methoxyflurane allowed effective control of both the depth and duration of anaesthesia. Recovery time was about 77 min. Sex differences generally were slight.

Ketamine-methoxyflurane anaesthesia for the mongolian gerbil, meriones unguiculatus