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The effect of reserpine and phenoxybenzamine pretreatment has been studied on copper acetate induced ovulation in rabbits. It has been observed that neither reserpine nor phenoxybenzamine prevented the ovulatory response of the copper salt. These findings indicate that copper induced ovulation does not appear to be mediated through the involvement of central adrenergic mechanisms.

EVIDENCE FOR NON-INVOLVEMENT OF CENTRAL CATECHOLAMINES IN COPPER ACETATE INDUCED OVULATION