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The effect of HPS (halofuginonepolystyrene sulfonate), a derivative of halofuginone with lower toxicity, on natural leucocytozoon and coccidial infection in broiler chickens was evaluated in a floor pen trial. The experiment was conducted from one day to 10 weeks of age. On leucocytozoon infection, HPS added to the diet was completely effective at 60 ppm, fairly effective at 40 ppm and ineffective at 20 ppm. On the other hand, HPS concentrations of 20 ppm, 40 ppm and 60 ppm were completely effective on coccidial infection. HPS at 40 ppm which corresponds to the recommended level of halofuginone (3 ppm) and at 60 ppm had no adverse effect on the weight gain in experimental birds.

Effect of HPS on leucocytozoon and coccidial infection in chickens.