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The throat cultures were collected on swabs from total number of 3,599 of first grade children of elementary schools in Otsu City in 1978. Beta-hemolytic streptococci were isolated from 628 of 3,599 children (17.4%). Group A strains were found in 403 of 628 children (64.2%). Thus the frequency of recovery of group A streptococci from the children was 11.2% in this study. The size of tonsils in children with positive cultures for group A streptococci and negative response of ASO was larger than tonsils of children with negative cultures for group a strains and negative ASO response, and were smaller than the tonsils of children with positive cultures for group A strains and with positive ASO response. On the 20th day after oral administration of 400,000 units of penicillin derivative, group A strains were eradicated from throats in 76.2% of the treated children.

japanese circulation journal

The Movement of Streptococcal Infection in Otsu City : Proceedings of the IV Conference on Prevention for Rheumatic Fever and Rheumatic Heart Disease, January 1979, Kyoto