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macological treatments for HFrEF including angiotensinconverting enzyme inhibitors, angiotensin receptor blockers, spironolactone and β-blocker have failed to improve the prognosis of HFpEF.4 Thus, patients with HFpEF have E pidemiologic studies indicate that almost half of heart failure (HF) patients have preserved ejection fraction and that this proportion has increased over time.1,2 Patients with HF with preserved ejection fraction (HFpEF) have better prognosis and are more likely to die from non-cardiovascular causes than those with HF with reduced ejection fraction (HFrEF).3 Also, standard pharArticle p ????

circulation journal

Beneficial Prognostic Effects of Statins in Heart Failure With Preserved Ejection Fraction (HFpEF) Patients ― HFpEF as a Manifestation of Systemic Disease ―