English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

LVNC in overall morbidity after 2 decades of follow-up, although late deaths occurred from fatal arrhythmias and thromboembolisms in the juvenile type, in addition to progressive congestive heart failure. Echocardiography video data were only available for 89 cases, therefore the noncompaction score was only reported for these. We excluded the remaining patients, including those who only had echocardiographic reports and photos, because noncompaction scores could not be accurately calculated. ICDs were implanted in LVNC patients who experienced severe ventricular arrhythmias that could not be well controlled by full doses of medication. Appropriate ICD discharge occurred in 25% and 50% of the patients in whom a defibrillator was implanted for primary and secondary prevention, respectively.5 Two patients with the infantile type and cardiac dysfunction died of ventricular arrhythmia; 3 patients with the juvenile type had sudden death resulting from fatal arrhythmias. In the study, none of the patients who reached an endpoint suffered from a NMD. Cardiac resynchronization therapy (CRT) was performed if patients showed left bundle branch block. One patient6 who had multiple hospitalizations despite full doses of several medications underwent CRT at 4 years of age, and cardiac function improved soon after, but worsened again 3 years later, and she underwent transplantation at 7 years old.

Survival in Young Patients With Noncompaction May Not Only Depend on Cardiac But Also on Neuromuscular Comorbidity ― Reply ―