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with a variety of other conditions in the early stage of atherosclerosis. For example, CAVI has been used to measure vascular status in untreated subclinical hypothyroidism to assess for cardiovascular events.5 After interventional treatment of ACS, risk stratification for atherosclerosis is clinically important. The main components are cardiovascular imaging and stress testing. Left ventricular ejection fraction is widely used after discharge to predict future hospitalization. Multiple imaging methods, including single photon emission computed tomography, for assessing left ventricular function are also available to assess prognosis.6 In addition, a noninvasive exercise stress test is widely performed after ACS to detect residual ischemia. Regarding patients with ACS, the contributions of this study to our knowledge are important. First, it is reasonable to use CAVI for risk stratification in patients after ACS. High CAVI (>8.325) was strongly associated with cardiovascular events and therefore we have to take care of the patients with high CAVI during follow-up. “Predicting Cardiovascular Events Is a Journey, Not a Destination.” The prevention of major cardiovascular and cerebrovascular events remains an essential public health problem.1 Atherosclerosis is a major contributor to development of cardiovascular diseases and is a major cause of mortality and morbidity in the older population. There are many vascular measurements for evaluating atherosclerosis in routine clinical practice, and a number of measures of vascular function [including measurement of brachial-ankle pulse wave velocity (ba-PWV), flow-mediated vasodilatation of the brachial artery induced by reactive hyperemia, and ankle-brachial blood pressure index] are available to access future cardiovascular risk.2 The cardioankle vascular index (CAVI) is a relatively novel index of aortic stiffness,3 and is obtained from measurement of ba-PWV and blood pressure.

Noninvasive Vascular Function Tests – Long Journey for Predicting Cardiovascular Events –