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all-cause group of deaths. Finally, the test used to diagnose obstructive sleep apnea (OSA) and CSA is not the gold standard for these diseases. In some cases, polygraphy is insufficient to rule out OSA when the respiratory events are mainly associated with arousals. Full-night polysomnography is recommended when polygraphy is “normal”.4 Some of the study patients diagnosed as “normal” may have had OSA but may not have been diagnosed correctly because of the test used in this study. In conclusion, a study with a better design and larger sample size may solve these issues.

Respiratory Therapy in Chronic Heart Failure Patients Complicated With Sleep-Disordered Breathing: Potential Study Bias