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In 21,105 patients with atrial fibrillation in the ENGAGE AF-TIMI 48 trial, edoxaban was non-inferior to warfarin in preventing thromboembolic events while reducing bleeding. We compared results in Japan with the rest of East Asia (EA), including China, Korea, and Taiwan.

Effects of Regional Differences in Asia on Efficacy and Safety of Edoxaban Compared With Warfarin – Insights From the ENGAGE AF-TIMI 48 Trial –