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Advancement in chemotherapy has significantly improved the prognosis of cancer patients. However, many anticancer drugs have serious cardiovascular side effects. We assessed doxorubicin-induced cardiac toxicity (DCT) during and after preoperative chemotherapy using gated (99m)Tc-hexakis-2-methoxyisobutylisonitrile (MIBI) single photon emission computed tomography (SPECT) in patients with malignant bone and soft tissue tumors.

circulation journal

Assessment of Doxorubicin Cardiac Toxicity Using Gated &lt;sup&gt;99m&lt;/sup&gt;Tc-Hexakis-2-Methoxyisobutylisonitrile Myocardial Single Photon Emission Computed Tomography