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Systolic abnormality, as well as diastolic dysfunction, is observed in patients with heart failure with preserved ejection fraction (HFPEF). However, the role of these 2 conditions in the transition from asymptomatic diastolic dysfunction to symptomatic heart failure remains unclear. We recently demonstrated that diastolic wall strain (DWS) inversely correlates to the myocardial stiffness constant.

circulation journal

Transition From Asymptomatic Diastolic Dysfunction to Heart Failure With Preserved Ejection Fraction - Roles of Systolic Function and Ventricular Distensibility -