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t is well established that patients with renal dysfunction have an increased frequency of cardiovascular events. This concept of cardiorenal association has come to be widely acknowledged after relevant cases were found not only abroad but also in Japan, as described in the Hisayama Study.1 The practical definition of renal dysfunction as “chronic kidney disease” (CKD), which is clinically applicable, has contributed much to the spread of this knowledge on cardiorenal association. But even though it is essential to include glomerular filtration rate (GFR) in the definition of CKD, urinary findings are not always used in many studies for CKD patients.

Significance of B-Type Natriuretic Peptide Measurement in Patients With Chronic Kidney Disease